Do racial differences exist in second-trimester maternal hCG levels? a study of 23 369 patients
| Autor: | Laurence Bussières, Claire Boué, Marie-Christine Pèlissier, F. Muller, Jean-François Oury, Serge Uzan, André Boué |
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| Rok vydání: | 1994 |
| Předmět: |
endocrine system
medicine.medical_specialty Down syndrome Black african medicine.drug_class Black People Chorionic Gonadotropin White People Human chorionic gonadotropin Asian People Pregnancy Reference Values Second trimester Prenatal Diagnosis Humans Medicine Prospective Studies Genetics (clinical) Gynecology business.industry Racial Groups Obstetrics and Gynecology medicine.disease Pregnancy Trimester Second Gestation Female Racial differences Down Syndrome Gonadotropin business hormones hormone substitutes and hormone antagonists |
| Zdroj: | Prenatal Diagnosis. 14:633-636 |
| ISSN: | 1097-0223 0197-3851 |
| DOI: | 10.1002/pd.1970140721 |
| Popis: | In Down syndrome screening by maternal serum human chorionic gonadotropin (hCG) determination at 15, 16, 17, and 18 weeks of gestation, we prospectively examined 23,369 sera from white (21,549), North African (970), black African (525), and Asian (325) patients. When expressed as multiples of the median (MOM), no difference was observed between white, North African, and black African patients. However, higher serum hCG concentrations were noted in Asians, for whom we therefore recommend correction of hCG values before calculation of the risk of Down syndrome. |
| Databáze: | OpenAIRE |
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