Neurocysticercosis in patients with active epilepsy in the tea garden community of Assam, Northeast India
| Autor: | S K Rajguru, Narayan Upadhyay, K Rekha Devi, Kanwar Narain, Debasish Borbora, Dibyajyoti Goswami |
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| Rok vydání: | 2021 |
| Předmět: |
Adult
Male medicine.medical_specialty Pediatrics Farms Adolescent Science 030231 tropical medicine Neurocysticercosis India Neurological examination Risk Assessment Article Young Adult 03 medical and health sciences Epilepsy 0302 clinical medicine Seroepidemiologic Studies Epidemiology Odds Ratio Prevalence medicine Humans Taeniasis In patient Child Multidisciplinary High prevalence Tea medicine.diagnostic_test business.industry Gardening Tea garden medicine.disease Cross-Sectional Studies Risk factors Acute Disease Medicine Female Parasitology Disease Susceptibility business Neurological disorders 030217 neurology & neurosurgery |
| Zdroj: | Scientific Reports, Vol 11, Iss 1, Pp 1-9 (2021) Scientific Reports |
| ISSN: | 2045-2322 |
| DOI: | 10.1038/s41598-021-86823-w |
| Popis: | Neurocysticercosis is a significant cause of epilepsy in the tropics. The present cross-sectional survey was conducted in the socioeconomically backward tea garden community of Assam to gauge the prevalence of neurocysticercosis in patients with active epilepsy and to determine the associated risk factors. In a door to door survey, a total of 1028 individuals from every fifth household of the study Teagarden were enrolled to identify self-reported seizure cases, followed by a neurological examination to confirm the diagnosis of active epilepsy. Patients with active epilepsy underwent clinical, epidemiological, neuroimaging (contrast-enhanced computerized tomography) and immunological evaluations to establish the diagnosis of neurocysticercosis. Clinically confirmed 53 (5.16%) active epilepsy were identified; 45 agreed to further assessment for neurocysticercosis and 19 (42.2%) cases fulfilled either definitive or probable diagnostic criteria for neurocysticercosis. Patients with epilepsy due to neurocysticercosis were more likely to suffer from taeniasis (20.0% vs 0.0%), rear pigs (57.9% vs 15.4%) or have pigs in their neighbourhood (78.9% vs 53.8%) relative to epileptic patients without neurocysticercosis. Rearing pigs (aOR 14.35, 95% CI: 3.98–51.75) or having pigs in the neighbourhood (aOR 12.34, 95% CI: 2.53–60.31) were independent risk factors of neurocysticercosis. In this community, the prevalence of taeniasis (adult worm infection) was 6.6% based on microscopy. The study reports a high prevalence of active epilepsy in the tea garden community of Assam and neurocysticercosis as its primary cause. The high prevalence of taeniasis is also a significant concern. |
| Databáze: | OpenAIRE |
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