The 'Doughnut' Sign in Cerebral Radioisotopic Images
| Autor: | J. G. McAfee, R. E. O'Mara, R. B. Chodos |
|---|---|
| Rok vydání: | 1969 |
| Předmět: |
Adult
Male Brain Diseases Pathology medicine.medical_specialty Brain Neoplasms business.industry Low activity Technetium 99mtc pertechnetate Brain tissue Middle Aged Cerebral Angiography Iodine Radioisotopes medicine Humans Female Radiology Nuclear Medicine and imaging Secondary tumors Neoplasm Metastasis Radionuclide Imaging Nuclear medicine business Pathological Volume concentration |
| Zdroj: | Radiology. 92:581-586 |
| ISSN: | 1527-1315 0033-8419 |
| DOI: | 10.1148/92.3.581 |
| Popis: | SOON AFTER the introduction of rectilinear scintillation scanning in 1955, focal organic lesions of the brain were delineated following the administration of various gamma-emitting compounds. Classically, these lesions have been identified as a locus of increased radioactivity within the low activity of normal brain tissue. This low concentration in normal brain has been attributed to an intact “blood-brain barrier” which becomes altered in pathological states, permitting a diffusion of radioactivity into the abnormal area. Various lesions, whether primary or secondary tumors, abscesses, granulomas, infarcts, or angiomatous malformations, have had a similar configuration on radioisotopic images. Since 1964, the use of large doses of short-lived agents, such as 99mTc pertechnetate, has resulted in a better delineation of these lesions. During the past eighteen months, the authors have noted a pattern which differs from the “classical” one, in which the zone of increased uptake contains a central core of de... |
| Databáze: | OpenAIRE |
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