Can Atlas-Based Auto-Segmentation Ever Be Perfect? Insights From Extreme Value Theory

Autor: Devis Peressutti, Tim Lustberg, Andre Dekker, Bas Schipaanboord, Johan van Soest, Wouter van Elmpt, Timor Kadir, Djamal Boukerroui, Mark Gooding
Přispěvatelé: RS: GROW - R3 - Innovative Cancer Diagnostics & Therapy, Promovendi ODB, Radiotherapie, Radiation Oncology
Jazyk: angličtina
Rok vydání: 2019
Předmět:
Zdroj: Ieee Transactions on Medical Imaging, 38(1), 99-106. IEEE
IEEE Transactions on Medical Imaging, 38(1), 99-106. Institute of Electrical and Electronics Engineers Inc.
ISSN: 0278-0062
Popis: Atlas-based segmentation is used in radiotherapy planning to accelerate the delineation of organs at risk (OARs). Atlas selection has been proposed to improve the performance of segmentation, assuming that the more similar the atlas is to the patient, the better the result. It follows that the larger the database of atlases from which to select, the better the results should be. This paper seeks to estimate a clinically achievable expected performance under this assumption. Assuming a perfect atlas selection, an extreme value theory has been applied to estimate the accuracy of single-atlas and multi-atlas segmentation given a large database of atlases. For this purpose, clinical contours of most common OARs on computed tomography of the head and neck ( ${N}=\textsf {316}$ ) and thoracic ( ${N}=\textsf {280}$ ) cases were used. This paper found that while for most organs, perfect segmentation cannot be reasonably expected, auto-contouring performance of a level corresponding to clinical quality could be consistently expected given a database of 5000 atlases under the assumption of perfect atlas selection.
Databáze: OpenAIRE