Usefulness of positron emission tomography/computed tomography in patients with valve-tube graft infection
| Autor: | Daniel García-Arribas, Aida Ortega Candil, Manuel Carnero-Alcázar, David Vivas, Carlos Pérez-García, Cristina Rodríguez Rey, Luis Maroto, José Luis Carreras, Isidre Vilacosta, Carmen Olmos, Cristina Fernández-Pérez, María Jesús Pérez Castejón |
|---|---|
| Rok vydání: | 2017 |
| Předmět: |
Adult
Male medicine.medical_specialty Prosthesis-Related Infections 030204 cardiovascular system & hematology Sensitivity and Specificity 03 medical and health sciences 0302 clinical medicine Fluorodeoxyglucose F18 Positron Emission Tomography Computed Tomography medicine Endocarditis Humans In patient 030212 general & internal medicine Prospective Studies Pathological Aortitis Positron Emission Tomography-Computed Tomography Aged Aged 80 and over medicine.diagnostic_test business.industry Reproducibility of Results Middle Aged medicine.disease Blood Vessel Prosthesis Homogeneous Positron emission tomography Spain Infective endocarditis Aortic Valve Heart Valve Prosthesis Female Vascular Grafting Radiology Radiopharmaceuticals Cardiology and Cardiovascular Medicine business |
| Zdroj: | Heart (British Cardiac Society). 104(17) |
| ISSN: | 1468-201X |
| Popis: | ObjectiveInfection of valved aortic grafts is a rare entity whose diagnosis remains challenging. Positron emission tomography (PET)/CT has become a criterion for the diagnosis of infective endocarditis (IE) in prosthetic valves, but its role on ascending aortic graft infections remains unclear. This study aims to assess the diagnostic value of PET/CT in patients with valved aortic graft infection.Methods12 episodes with a valved aortic graft who had undergone a PET/CT due to suspicion of IE were prospectively included (group I) and compared with five controls free of infection who underwent PET/CT for other reasons (group II). Pathological uptake of 18F-fluorodeoxyglucose (FDG) and its pattern at the prosthetic valve and aortic graft were studied.ResultsDiagnosis of IE was confirmed in 9 out of 12 episodes of group I. 18F-FDG uptake was detectable in eight out of nine cases with a final diagnosis of IE. The most repeated pattern of uptake was homogeneous around the valve and heterogeneous around the tube. There was one false-negative study. Of the three patients in which IE was ruled out, there were two false positives and one true negative. In group II, there were three patients with a positive PET/CT study, two of them had active aortitis and the third was considered false positive.Conclusions18F-FDG PET/CT shows high sensitivity in the detection of infected aortic grafts. Thus, this technique should be considered in the diagnostic work-up of patients with suspicion of aortic graft infection. However, further validation of this approach is needed. |
| Databáze: | OpenAIRE |
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