Relationship Between Upper Airway and Inspiratory Pump Muscle Force in Obstructive Sleep Apnea
| Autor: | Cathryn M. Jensen, Peter R. Eastwood, Kelly L. Shepherd, David R. Hillman, Kathleen J. Maddison |
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| Rok vydání: | 2006 |
| Předmět: |
Adult
Male Pulmonary and Respiratory Medicine Polysomnography Critical Care and Intensive Care Medicine Functional residual capacity Tongue Reference Values Risk Factors Respiratory muscle Humans Medicine Muscle Strength Obesity Wakefulness Aged Sleep Apnea Obstructive Genioglossus medicine.diagnostic_test business.industry Sleep apnea Middle Aged medicine.disease Respiratory Muscles respiratory tract diseases Residual Volume Obstructive sleep apnea Inhalation Apnea–hypopnea index Anesthesia Dilator Female Cardiology and Cardiovascular Medicine business |
| Zdroj: | Chest. 130:1757-1764 |
| ISSN: | 0012-3692 |
| DOI: | 10.1378/chest.130.6.1757 |
| Popis: | Background Upper airway (UA) patency during inspiration is determined by the balance between dilating forces generated by UA dilator muscle activity and collapsing forces related to the decreased intraluminal pressure that accompanies flow generated by inspiratory muscle activity. It is possible that the relative strengths of UA dilator and inspiratory pump muscles could be an important determinant of the susceptibility to UA collapse during sleep ( ie , obstructive sleep apnea [OSA]). Methods Measurements of tongue protrusion (TP) force and maximum inspiratory pressure (P i max) were obtained in 94 patients admitted for overnight polysomnography for suspected OSA, quantified by apnea-hypopnea index (AHI). Results There was a direct linear relationship between TP force and P i max ( r 2 = 0.37, p i max (greater than group 90th percentile, 0.027 kg/cm H 2 O) appeared to protect against OSA, as moderate-to-severe OSA (AHI > 20/h) was not observed in any individual with a ratio above this threshold. AHI was not linearly related to TP force, P i max, or the ratio of TP force to P i max. Conclusions UA muscle strength is linearly related to inspiratory pump muscle strength. The ratio of UA muscle strength (TP force) and inspiratory pump muscle strength (P i max) was not different between individuals with and without OSA; however, a high wakeful ratio of TP force to P i max appears to be associated with a reduced propensity to moderate-to-severe OSA. |
| Databáze: | OpenAIRE |
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