Interlaboratory comparison of serum vitamin B12 assay
| Autor: | S M Lewis, A V Hoffbrand, P G Ward, D L Mollin |
|---|---|
| Rok vydání: | 1980 |
| Předmět: |
Radioisotope Dilution Technique
Chromatography education Microbiological assay General Medicine Biology United Kingdom Pathology and Forensic Medicine Lactobacillus Vitamin B 12 Biochemistry Evaluation Studies as Topic Euglena gracilis Humans Biological Assay Vitamin B12 Radioisotope dilution technique Laboratories Serum vitamin b12 human activities Research Article |
| Zdroj: | Journal of Clinical Pathology. 33:243-248 |
| ISSN: | 0021-9746 |
| DOI: | 10.1136/jcp.33.3.243 |
| Popis: | The results have been compared of microbiological and radioisotope dilution (RID) assay of serum vitamin B12 by participants in national interlaboratory trials in Britain. There was wide variation between the individual participants, especially marked in the L. leichmannii microbiological assay and in the RID methods, whereas excellent correlation, reproducibility, and recovery were obtained in reference laboratories by microbiological assay with both E. gracilis and L. leichmannii. In general, RID gave higher results than microbiological assay. The need for suitable reference sera is emphasised. |
| Databáze: | OpenAIRE |
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