A clinical decision rule for streptococcal pharyngitis management: An update
| Autor: | Seyedehsara Bayesh, Esfandiar Matini, Saeedeh TarvijEslami, Yasaman Omaraee, Hosain Nasirian |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2017 |
| Předmět: |
medicine.medical_specialty
Common disease lcsh:Medicine Throat culture 03 medical and health sciences 0302 clinical medicine lymph nodes streptococcal Throat Internal medicine Medicine 030212 general & internal medicine Clinical decision medicine.diagnostic_test business.industry lcsh:R pharyngitis exudate Predictive value Pharyngitis Surgery medicine.anatomical_structure Positive culture Original Article medicine.symptom business 030217 neurology & neurosurgery erythema |
| Zdroj: | Journal of Laboratory Physicians, Vol 9, Iss 02, Pp 116-120 (2017) Journal of Laboratory Physicians |
| ISSN: | 0974-7826 0974-2727 |
| DOI: | 10.4103/0974-2727.199635 |
| Popis: | PURPOSE: Group A streptococcal (GAS) pharyngitis is a common disease worldwide. We aimed to establish a pragmatic program as a clinical decision rule for GAS pharyngitis diagnosis. MATERIALS AND METHODS: This article derived from a research project on children aged 6–15 years. Five hundred and seventy-one children met the enrollment criteria on whom throat culture and validities of clinical findings were assessed in positive and negative throat culture groups. RESULTS: Positive GAS throat culture group included 99 (17.3%) patients with a positive culture. Negative GAS throat culture group included 472 (82.6%) patients. Exudate or enlarged tender nodes each one had 63% and 68% sensitivity and 31.5% and 37.5% specificity with a high percentage of negative predictive value (NPV) 80.54% and 85.09%, respectively. Sequence test revealed validities of exudate plus enlarged nodes at 43.62% sensitivity and 57.19% specificity with 83% NPV. CONCLUSIONS: High NPV of 83% indicated that similar prevalence in the absence of either exudate or enlarged tender lymph nodes. Probability of GAS negative throat cultures among children suspected of GAS pharyngitis was 83% and would correctly not receive inopportune antibiotics. |
| Databáze: | OpenAIRE |
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