Assisted reproduction in hepatitis carrier couples
| Autor: | Jennifer Sze Man Mak, Terence T. Lao |
|---|---|
| Rok vydání: | 2020 |
| Předmět: |
Adult
Hepatitis B virus media_common.quotation_subject Fertility Fertilization in Vitro Virus 03 medical and health sciences 0302 clinical medicine Hepatitis B Chronic Ovulation Induction Pregnancy medicine Humans 030212 general & internal medicine reproductive and urinary physiology media_common Hepatitis 030219 obstetrics & reproductive medicine High prevalence Hepatitis B Surface Antigens business.industry Transmission (medicine) virus diseases Obstetrics and Gynecology General Medicine medicine.disease Hepatitis B Follicular fluid digestive system diseases Infectious Disease Transmission Vertical Semen Analysis Viral replication Infertility embryonic structures Immunology DNA Viral Female Reproduction business |
| Zdroj: | Best practiceresearch. Clinical obstetricsgynaecology. 68 |
| ISSN: | 1532-1932 |
| Popis: | Chronic Hepatitis B virus (HBV) infection is endemic worldwide, and the prevalence is especially high in the Asia-Pacific regions. Despite its high prevalence, the literature regarding the impact of HBV infection on subfertility and fertility treatment remains limited and conflicting. Latest studies do not suggest any detrimental effect of HBV infection on the outcome of IVF/ICSI treatment in women having chronic HBV infection. There is evidence that HBV exists in ovarian tissue including oocyte and follicular fluid, and therefore has the potential risk of transmission to the embryo, which can explain the finding of vertical transmission despite immunoprophylaxis. Most recently, we have observed the evidence of HBV viral replication in female HBV carriers undergoing IVF/ICSI treatment. This raises the question of whether antiviral medication should be administered during ovarian stimulation in IVF/ICSI treatment cycles for women with chronic HBV infection to help reduce the chance of vertical transmission. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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