Direct analysis of six antibiotics in wastewater samples using rapid high-performance liquid chromatography coupled with diode array detector: A chemometric study towards green analytical chemistry
| Autor: | Kazem Kargosha, Amir Salemi, Masoumeh Rashvand, Hadi M. Esfahani, Maryam Vosough |
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| Rok vydání: | 2015 |
| Předmět: |
Ofloxacin
Sulfamerazine Analyte Chromatography Sulfamethoxazole Chemistry Analytical chemistry Amoxicillin Sulfadiazine Green Chemistry Technology Wastewater High-performance liquid chromatography Anti-Bacterial Agents Analytical Chemistry Matrix (chemical analysis) Chromatography detector Metronidazole medicine Sewage treatment Effluent Chromatography High Pressure Liquid Water Pollutants Chemical medicine.drug |
| Zdroj: | Talanta. 135:7-17 |
| ISSN: | 0039-9140 |
| Popis: | In this work, a rapid HPLC–DAD method has been developed for the analysis of six antibiotics (amoxicillin, metronidazole, sulfamethoxazole, ofloxacine, sulfadiazine and sulfamerazine) in the sewage treatment plant influent and effluent samples. Decreasing the chromatographic run time to less than 4 min as well as lowering the cost per analysis, were achieved through direct injection of the samples into the HPLC system followed by chemometric analysis. The problem of the complete separation of the analytes from each other and/or from the matrix ingredients was resolved as a posteriori. The performance of MCR/ALS and U-PLS/RBL, as second-order algorithms, was studied and comparable results were obtained from implication of these modeling methods. It was demonstrated that the proposed methods could be used promisingly as green analytical strategies for detection and quantification of the targeted pollutants in wastewater samples while avoiding the more complicated high cost instrumentations. |
| Databáze: | OpenAIRE |
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