The effect of endometrial injury on implantation and clinical pregnancy rates

Autor:	Dan Levin, Lilia Barzilay, Joseph Hasson, Baris Ata, Yuval Or, Benny Almog, Aviad Cohen
Rok vydání:	2017
Předmět:	Adult medicine.medical_specialty Pregnancy Rate Endocrinology Diabetes and Metabolism Clinical pregnancy Fertilization in Vitro Logistic regression Endometrium 03 medical and health sciences 0302 clinical medicine Endocrinology Implantation failure Pregnancy Physical Stimulation Ongoing pregnancy Humans Medicine Embryo Implantation 030212 general & internal medicine Retrospective Studies Gynecology 030219 obstetrics & reproductive medicine medicine.diagnostic_test business.industry Obstetrics Case-control study Obstetrics and Gynecology Embryo Transfer medicine.disease Catheter Case-Control Studies embryonic structures Female Stress Mechanical business Endometrial biopsy
Zdroj:	Gynecological Endocrinology. 33:779-782
ISSN:	1473-0766 0951-3590
Popis:	To assess the effect of endometrial scratching (ES) on in vitro fertilization-embryo transfer outcome (IVF-ET) Materials and methods: Retrospective matched case control study including all fresh IVF cycles performed between January 2006 and December 2012 at an academic IVF center. ES with an endometrial biopsy catheter was performed in the cycle preceding the index IVF cycle. Patients (n = 238) were pair matched with controls according to age, number of previous failed IVF cycles and number of embryos transferred.Demographic and cycle characteristics were comparable in all of the following: age, number of previous cycles, number of collected oocyte, number of embryos transferred and quality of transferred embryos. Implantation, clinical and ongoing pregnancy rates were comparable in both groups (28%, 34% and 18.4% vs 30%, 40.3% and 29%, in ES group and controls, respectively). Logistic regression analysis found no significant association between ES and pregnancy rate.Mechanical endometrial stimulation did not improve implantation and pregnancy rates. Furthermore, no factors that may predict which patients could benefit from ES were identified. Further prospective studies are warranted to evaluate possible benefits in different subsets of patients such as patients with recurrent implantation failures.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9b981d846f1d5cd1e896e895c1dee1d3 https://doi.org/10.1080/09513590.2017.1318369 Zobrazit plný text záznamu Plný text ve formátu PDF Plný text ve formátu HTML
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