Acute versus chronic conditions for studies of fetal nutrient requirements: applicability to the human
| Autor: | Adrien Schaefer, J. Lefaivre, R. Hsiung, François Piquard, J.P. Barlet, Pascal Haberey, Pierre Dellenbach |
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| Rok vydání: | 1986 |
| Předmět: |
Blood Glucose
medicine.medical_specialty Placenta Nutrient Fetus Species Specificity Pregnancy Internal medicine medicine Blood lactate Animals Humans Lactic Acid Sheep business.industry Cesarean Section Obstetrics and Gynecology Endocrinology medicine.anatomical_structure Glucose Reproductive Medicine Lactates Female Fetal nutrition business Developmental Biology |
| Zdroj: | Placenta. 7(2) |
| ISSN: | 0143-4004 |
| Popis: | Summary In order to validate results obtained in ‘acute’ versus ‘chronic’ experimental conditions, two fetal sheep nutrients, lactate and glucose, have been determined in ‘acute’ conditions and compared with the ‘chronic’ data in the literature. Maternal and fetal blood glucose in ‘acute’ conditions was in the range of published ‘chronic’ data. Fetal blood lactate was similar in ‘acute’ and during ‘chronic’ conditions. Maternal and fetal veno-arterial (VA) differences were in the same direction in ‘acute’ and in ‘chronic’ conditions for both lactate and glucose and of the same magnitude for lactate. For glucose, a good relationship was observed between umbilical VA differences and maternal arterial concentrations for all ‘acute’ and ‘chronic’ values. Thus no fundamental differences appear in the results obtained in ‘acute’ or during ‘chronic’ conditions. The applicability of such animal results to the human and the use of acute conditions to study fetal nutrition in the human are discussed. |
| Databáze: | OpenAIRE |
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