Structure-property relationships on recrystallized β-cyclodextrin solvates: A focus on X-ray diffractometry, FTIR and thermal analyses
| Autor: | Christine A. Lucan, Simelda Elena Zippenfening, Maria Rada, Alina Heghes, Daniel I. Hădărugă, Cornelia Muntean, Geza Bandur, Gabriela Popescu, Nicoleta G. Hădărugă, Mircea Riviş, Mihai Medeleanu, Ariana Velciov |
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| Rok vydání: | 2020 |
| Předmět: |
Octanol
Recrystallization (geology) Materials science Polymers and Plastics Spectrophotometry Infrared Infrared spectroscopy 02 engineering and technology 010402 general chemistry 01 natural sciences Crystal Crystallinity chemistry.chemical_compound X-Ray Diffraction Spectroscopy Fourier Transform Infrared Materials Chemistry Thermal analysis Calorimetry Differential Scanning Ethanol Organic Chemistry beta-Cyclodextrins Water 021001 nanoscience & nanotechnology 0104 chemical sciences Solvent Partition coefficient chemistry Solubility Thermogravimetry Solvents Physical chemistry 0210 nano-technology Crystallization Hydrophobic and Hydrophilic Interactions |
| Zdroj: | Carbohydrate polymers. 265 |
| ISSN: | 1879-1344 |
| Popis: | The goal of the study was to evaluate the influence of the solvent properties on the crystal characteristics of β-cyclodextrin (β-CD) recrystallized from alcohol-water solvent mixtures, with possible applications for the preparation, purifying and complexation of β-CD. For the first time, structure-property relationships (QSPRs) between the hydrophobicity of alcohols or dielectric constant of solvents used for recrystallization of β-CD and its properties (such as crystallinity index, CI) have been obtained. Recrystallized β-CD from water and C1-C4 alcohol-water solutions provide β-CD with higher CI values of 99.4(±5.9)% for ethanol-water (1:4, v/v) as recrystallizing system. This property has a parabolic variation with the logP (octanol/water partition coefficient) of the alcohol (r2 = 0.998). Solvent parameters also influence the β-CD crystal characteristics, as was demonstrated by X-ray diffractometry refinement, infrared spectroscopy and thermal analyses. |
| Databáze: | OpenAIRE |
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