High trans but not saturated fat beverage causes an acute reduction in postprandial vascular endothelial function but not arterial stiffness in humans
| Autor: | Kaitlyn Dubishar, Jordan R Witmer, Lauren J Points, Janie Myers, Lyndsey E. DuBose, Gary L. Pierce, Kyle Siefers, Catherine A. Chenard, Abbi D. Lane-Cordova |
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| Rok vydání: | 2016 |
| Předmět: |
Adult
Male medicine.medical_specialty Time Factors Brachial Artery Saturated fat Administration Oral Flow mediated dilation 030209 endocrinology & metabolism 030204 cardiovascular system & hematology Article Beverages 03 medical and health sciences Vascular Stiffness 0302 clinical medicine Risk Factors Internal medicine medicine Humans Plant Oils Pulse wave velocity Nitrites Cross-Over Studies Nitrates business.industry High fat diet Middle Aged Trans Fatty Acids Postprandial Period medicine.disease Iowa Soybean Oil Vasodilation Endocrinology Postprandial Cardiovascular Diseases Coconut Oil Arterial stiffness Female Endothelium Vascular Insulin Resistance Cardiology and Cardiovascular Medicine business Biomarkers |
| Zdroj: | Vascular Medicine. 21:429-436 |
| ISSN: | 1477-0377 1358-863X |
| Popis: | A diet high in trans-fatty acids (TFAs) is associated with a higher risk of cardiovascular disease (CVD) than a diet high in saturated fatty acids (SFAs), but the mechanisms remain unclear. We hypothesized that a beverage high in TFAs would cause a larger reduction in postprandial endothelial function and an increase in arterial stiffness, in part from greater reductions in insulin sensitivity, compared with a beverage high in SFAs. Eleven healthy adults (aged 47±5 years) ingested a warm test beverage (520 kcal, 56 g total fat, 5 g carbohydrate, 1 g protein) high in either TFAs or SFAs in a randomized cross-over study. Ingestion of the beverage high in TFAs ( p |
| Databáze: | OpenAIRE |
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