Coronary flow response to remote ischemic preconditioning is preserved in old cardiac patients
| Autor: | Elpidio Santillo, Fabrizio Balestrini, Monica Migale, Fabrizia Lattanzio, Raffaele Antonelli-Incalzi, Demetrio Postacchini, Silvia Bustacchini |
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| Rok vydání: | 2017 |
| Předmět: |
Male
Aging medicine.medical_specialty Ischemia 030204 cardiovascular system & hematology 03 medical and health sciences 0302 clinical medicine Internal medicine medicine Humans 030212 general & internal medicine Aged Ultrasonography Coronary flow Aged 80 and over Cardioprotection Cardiac Rehabilitation business.industry Ultrasound Heart medicine.disease Coronary Vessels medicine.anatomical_structure Echocardiography Heart failure Ischemic Preconditioning Myocardial Cardiology Ischemic preconditioning Female Functional status Geriatrics and Gerontology business Blood Flow Velocity Artery |
| Zdroj: | Aging Clinical and Experimental Research. 30:829-837 |
| ISSN: | 1720-8319 |
| DOI: | 10.1007/s40520-017-0845-1 |
| Popis: | The effect of remote ischemic preconditioning (RIPC) on coronary flow in elderly cardiac patients has not been investigated yet. Thus, we aimed to study the change of coronary flow subsequent to RIPC in old patients with heart diseases and to identify its main correlates. Ninety-five elderly patients (aged ≥ 65 years) accessing cardiac rehabilitation ward underwent transthoracic ultrasound evaluation of peak diastolic flow velocity of left anterior descending artery. Measurements of coronary flow velocity were performed on baseline and after an RIPC protocol (three cycles of 5 min ischemia of right arm alternating 5 min reperfusion). Differences between subjects with coronary flow velocity change over or equal the 75° percentile (high-responders) and subjects with a coronary flow velocity change under the 75° percentile (low-responders) were assessed. In enrolled elderly heart patients, coronary flow velocity significantly augmented from baseline after RIPC [0.23 m/s (0.18–0.28) vs 0.27 m/s (0.22–0.36); p |
| Databáze: | OpenAIRE |
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