Lafora's Disease
| Autor: | Urbaan J. G. van Haelst, Joop L. Slooff, Fons J. M. Gabreëls, Henk H. J. Jaspar, Willy O. Renier, Bert L. S. M. Busard |
|---|---|
| Rok vydání: | 1986 |
| Předmět: |
Pathology
medicine.medical_specialty Adolescent Epilepsies Myoclonic Autopsy Apocrine sweat gland Inclusion bodies Arts and Humanities (miscellaneous) Humans Medicine Eccrine sweat gland Skin Inclusion Bodies integumentary system medicine.diagnostic_test business.industry Brain biopsy Brain Anatomy Axilla medicine.anatomical_structure Skin biopsy Female Neurology (clinical) business Duct (anatomy) |
| Zdroj: | Archives of Neurology. 43:296 |
| ISSN: | 0003-9942 |
| DOI: | 10.1001/archneur.1986.00520030082023 |
| Popis: | • A patient had the clinical and neuropathologic signs of Lafora's disease. Skin biopsy specimens from the midcalf area confirmed earlier findings by showing numerous periodic acid-Schiff-positive inclusion bodies in eccrine sweat gland duct cells. In our patient, however, inclusion bodies were more abundantly present in the apocrine sweat gland duct cells of the axilla skin. In brain biopsy specimens and autopsy material the same periodic acid-Schiff-positive inclusion bodies were found. From these data it can be stated that skin biopsy of the axilla is the method of first choice in confirming the diagnosis. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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