Early hemodynamics and clinical outcomes of isolated aortic valve replacement with stentless or transcatheter valve in intermediate-risk patients

Autor: Gianluigi Bisleri, Thierry Folliguet, Christina Schäfer, Theodor Fischlein, Roberto Di Bartolomeo, Claudio Muneretto, Benjamin Claus, Lorenzo Di Bacco, Alberto Repossini, Herko Grubitzsch, Bruno Passaretti, Laura Giroletti, Giuseppe Santarpino, François Laborde
Přispěvatelé: Repossini, Alberto, Di Bacco, Lorenzo, Passaretti, Bruno, Grubitzsch, Herko, Schã¤fer, Christina, Claus, Benjamin, Giroletti, Laura, Folliguet, Thierry, Bisleri, Gianluigi, Fischlein, Theodor, Santarpino, Giuseppe, Di Bartolomeo, Roberto, Laborde, Franã§oi, Muneretto, Claudio
Rok vydání: 2016
Předmět:
Male
Time Factors
Hemodynamics
intermediate risk
030204 cardiovascular system & hematology
stentless aortic prosthesi
stentless aortic prosthesis
haemodynamic
0302 clinical medicine
Aortic valve replacement
Risk Factors
transcatheter aortic valve
030212 general & internal medicine
Cardiac skeleton
Hospital Mortality
Heart Valve Prosthesis Implantation
education.field_of_study
Prognosis
Europe
Survival Rate
Echocardiography
Aortic Valve
Heart Valve Prosthesis
Cardiology
Female
transcatheter aortic valves
Cardiology and Cardiovascular Medicine
Pulmonary and Respiratory Medicine
medicine.medical_specialty
haemodynamics
small aortic annulus
Surgery
Population
Prosthesis Design
Transcatheter Aortic Valve Replacement
03 medical and health sciences
Internal medicine
medicine
Humans
education
Aged
Retrospective Studies
business.industry
small aortic annulu
Odds ratio
Aortic Valve Stenosis
medicine.disease
Confidence interval
Implant
Intermediate risk
business
Follow-Up Studies
Zdroj: The Journal of thoracic and cardiovascular surgery. 153(3)
ISSN: 1097-685X
Popis: Objective Stentless aortic valves have been developed to overcome obstructive limitations associated with stented bioprostheses. The aim of the current multi-institutional study was to compare hemodynamics of transcatheter (TAVR) and the Freedom SOLO Stentless (FS) valve in an intermediate risk population undergoing surgical aortic valve replacement. Methods From 2010 to 2014, 420 consecutive patients underwent isolated surgical aortic valve replacement with FS and 375 patients underwent TAVR. Only patients with intermediate operative risk (Society of Thoracic Surgeons score 4-10) and small aortic annulus (≤23 mm) were included. After a propensity matched analysis 142 patients in each group were selected. Thirty-day postoperative clinical and echocardiographic parameters were evaluated. Results Mean prosthesis diameter was 22.2 ± 0.9 mm for FS and 22.4 ± 1.0 mm for TAVR. In-hospital mortality was 2.1% for FS and 6.3% for TAVR (P = .02). Postoperative FS peak gradients were 19.1 ± 9.6 mm Hg (mean 10.8 ± 5.9 mm Hg); TAVR peak gradients were 20.2 ± 9.5 mm Hg (mean 10.7 ± 6.9 mm Hg) P = .57 (P = .88). Postoperative effective orifice area was 1.93 ± 0.52 cm2for FS and 1.83 ± 0.3 cm2for TAVR (P = .65). There was no prostheses-patient mismatch in either group. Postoperative grade 2-3 paravalvular leak was present in 3.5% for TAVR and 0.7% for FS. Postoperative permanent pacemaker implant rate was 12% for TAVR and only 1 case (0.7%) in the FS group (PÂ
Databáze: OpenAIRE