Characterization of the Airflow within an Average Geometry of the Healthy Human Nasal Cavity
| Autor: | Brüning, Jan, Hildebrandt, Thomas, Heppt, Werner, Schmidt, Nora, Lamecker, Hans, Szengel, Angelika, Amiridze, Natalja, Ramm, Heiko, Bindernagel, Matthias, Zachow, Stefan, Goubergrits, Leonid |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2020 |
| Předmět: |
Adult
Male Wall Shear Stresses (WSS) Healthy Human Nasal Cavity Cross-Sectional Areas (CSA) Computational science lcsh:R lcsh:Medicine Models Biological Article Medical research Respiratory signs and symptoms Humans Female lcsh:Q Nasal Cavity Tomography X-Ray Computed lcsh:Science Biomedical engineering 600 Technik Medizin angewandte Wissenschaften::610 Medizin und Gesundheit::610 Medizin und Gesundheit Algorithms Retrospective Studies Work of Breathing |
| Zdroj: | Scientific Reports, Vol 10, Iss 1, Pp 1-12 (2020) Scientific Reports |
| ISSN: | 2045-2322 |
| DOI: | 10.1038/s41598-020-60755-3 |
| Popis: | This study’s objective was the generation of a standardized geometry of the healthy nasal cavity. An average geometry of the healthy nasal cavity was generated using a statistical shape model based on 25 symptom-free subjects. Airflow within the average geometry and these geometries was calculated using fluid simulations. Integral measures of the nasal resistance, wall shear stresses (WSS) and velocities were calculated as well as cross-sectional areas (CSA). Furthermore, individual WSS and static pressure distributions were mapped onto the average geometry. The average geometry featured an overall more regular shape that resulted in less resistance, reduced WSS and velocities compared to the median of the 25 geometries. Spatial distributions of WSS and pressure of the average geometry agreed well compared to the average distributions of all individual geometries. The minimal CSA of the average geometry was larger than the median of all individual geometries (83.4 vs. 74.7 mm²). The airflow observed within the average geometry of the healthy nasal cavity did not equal the average airflow of the individual geometries. While differences observed for integral measures were notable, the calculated values for the average geometry lay within the distributions of the individual parameters. Spatially resolved parameters differed less prominently. |
| Databáze: | OpenAIRE |
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