Girdling effect of nonstimulated cardiomyoplasty on left ventricular function
| Autor: | Elias Kaczer, Jeffrey M. Pearl, Richard S. Gerber, Jeffrey B. Sack, Eli R. Capouya, Hillel Laks, Alon S. Aharon, Paul Chang, Steven W. Barthel, Davis C. Drinkwater |
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| Rok vydání: | 1993 |
| Předmět: |
Pulmonary and Respiratory Medicine
medicine.medical_specialty Heart disease medicine.medical_treatment Heart Ventricles Hemodynamics Ventricular Function Left Dogs Internal medicine medicine Animals Prospective Studies Cardiac Surgical Procedures Heart Failure Ejection fraction business.industry Muscles Latissimus dorsi muscle Cardiac Pacing Artificial Stroke Volume Stroke volume medicine.disease medicine.anatomical_structure Ventricle Echocardiography Heart failure cardiovascular system Cardiology Surgery Cardiology and Cardiovascular Medicine business Cardiomyoplasty Dilatation Pathologic |
| Zdroj: | The Annals of thoracic surgery. 56(4) |
| ISSN: | 0003-4975 |
| Popis: | The precise hemodynamic effects of latissimus dorsi cardiomyoplasty have not been well characterized. We prospectively studied 11 mongrel dogs using a rapid ventricular pacing model of congestive heart failure. Six dogs received a nonstimulated left latissimus dorsi cardiomyoplasty wrap, and 5 control dogs were paced only. Two-dimensional transthoracic echocardiography was performed on all dogs at baseline and then weekly for 4 weeks. Measurements obtained included left ventricular diameters, lengths, volumes, and ejection fractions. Progressive left ventricular enlargement, increase in volumes, and worsening ejection fractions developed in both groups. However, less left ventricular dilatation and higher ejection fractions were seen in dogs that received a cardiomyoplasty wrap. A nonstimulated cardiomyoplasty wrap significantly attenuated the degree of left ventricular enlargement, increase in left ventricular volumes, and decrease in ejection fraction in a rapid pacing model of congestive heart failure. Apart from its effect on systolic augmentation with a stimulated muscle wrap, cardiomyoplasty may have an important "girdling" effect on the left ventricle that prevents dilatation and deterioration of left ventricular function. |
| Databáze: | OpenAIRE |
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