A taste of individualized medicine: physicians' reactions to automated genetic interpretations
| Autor: | Hallvard Lærum, Sara Bremer, Thomas Grünfeld, Stein Bergan |
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| Rok vydání: | 2014 |
| Předmět: |
Background information
Decision support system Attitude of Health Personnel media_common.quotation_subject Health Informatics Brief Communication User-Computer Interface Nursing Human–computer interaction Physicians Cytochrome P-450 CYP3A Electronic Health Records Humans Medicine Genetic Testing Precision Medicine media_common Genetic testing medicine.diagnostic_test Attitude to Computers business.industry Medical record Taste (sociology) Kidney Transplantation Transparency (behavior) Pharmacogenetics Personalized medicine User interface business Algorithms Immunosuppressive Agents |
| Zdroj: | Journal of the American Medical Informatics Association. 21:e143-e146 |
| ISSN: | 1527-974X 1067-5027 |
| Popis: | The potential of pharmacogenomics is well documented, and functionality exploiting this knowledge is about to be introduced into electronic medical records. To explore physicians' reactions to automatic interpretations of genetic tests, we built a prototype with a simple interpretive algorithm. The algorithm was adapted to the needs of physicians handling immunosuppressive treatment during organ transplantation. Nine physicians were observed expressing their thoughts while using the prototype for two patient scenarios. The computer screen and audio were recorded, and the qualitative results triangulated with responses to a survey instrument. The physicians' reactions to the prototype were very positive; they clearly trusted the results and the theory behind them. The explanation of the algorithm was prominently placed in the user interface for transparency, although this design led to considerable confusion. Background information and references should be available, but considerably less prominent than the result and recommendation. |
| Databáze: | OpenAIRE |
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