Comparative study of screening techniques for antibacterial activity evaluation of plant crude extracts and pure compounds

Autor:	Wilson Roberto Cunha, Carlos Henrique Gomes Martins, Everton Giovanni Alves, Luciana Assirati Casemiro, Adriana H. C. Vinholis, Márcio Luis Andrade e Silva, Niege Araçari Jacometti Cardoso Furtado
Jazyk:	portugalština
Rok vydání:	2008
Předmět:	Screening techniques antimicrobial activity Traditional medicine biology plant extracts Chemistry Melastomataceae General Chemistry Antibacterial activity biology.organism_classification Miconia rubiginosa screening methods
Zdroj:	Química Nova v.31 n.5 2008 Química Nova Sociedade Brasileira de Química (SBQ) instacron:SBQ Química Nova, Volume: 31, Issue: 5, Pages: 1224-1229, Published: 2008
Popis:	In this work, the effectiveness of four screening techniques (three techniques of the diffusion method and one microdilution broth method) were compared. Evaluated were the ethanolic and dichloromethanic extracts of Miconia rubiginosa (Melastomataceae) against six standard bacteria (ATCC). The results showed statistical disagreement among the three diffusion techniques. Among the diffusion techniques, the well technique displayed the best result. However the microdilution broth method demonstrated to be the most adequate method to evaluate the antibacterial activity of plant crude extracts and pure compounds when compared to the other methodologies.
Databáze:	OpenAIRE
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