Membrane differentiation in rat dorsal root ganglia and possible consequences for back pain
| Autor: | Marshall Devor, Malu Obermayer |
|---|---|
| Rok vydání: | 1984 |
| Předmět: |
Male
Neural Conduction Stain Ion Channels Dorsal root ganglion Ganglia Spinal medicine Back pain Animals Axon Ion channel Staining and Labeling business.industry General Neuroscience Sodium Anatomy Rats Staining Membrane medicine.anatomical_structure nervous system Back Pain Soma medicine.symptom business Ferrocyanides |
| Zdroj: | Neuroscience Letters. 51:341-346 |
| ISSN: | 0304-3940 |
| DOI: | 10.1016/0304-3940(84)90400-2 |
| Popis: | The ferric ion-ferrocyanide staining procedure (Quick and Waxman, J. Neurol. Sci., 31 (1977) 1-11), believed to label selectively membrane regions with high sodium-channel content and hence elevated electrical excitability, was used to stain lower lumbar dorsal root ganglion (DRG) neurons in adult rats. In many such cells, including both large type A neurons and small type B neurons, the initial segment of the stem axon and a variable portion of the adjacent soma surface stained heavily. It is suggested that this membrane specialization represents a zone of elevated excitability which may contribute to ectopic impulse generation in DRGs. |
| Databáze: | OpenAIRE |
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