Association of blood lipids with coronary artery plaque among Saudi patients referred to computed tomography
| Autor: | Hamad Al Qahtani, Sumaya Al Helali, Muhammad Hanif, Abdullah Belfageih, Sameer Al Dulikan, Ahmad AlMajed, Nura Alshugair |
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| Rok vydání: | 2021 |
| Předmět: |
Adult
Male medicine.medical_specialty Saudi Arabia Blood lipids Computed tomography Coronary Artery Disease Severity of Illness Index Internal medicine Medicine Humans Triglycerides Retrospective Studies medicine.diagnostic_test business.industry Cholesterol HDL Middle Aged Plaque Atherosclerotic medicine.anatomical_structure Cross-Sectional Studies Cardiology Female business Cardiology and Cardiovascular Medicine Tomography X-Ray Computed Artery |
| Zdroj: | BMC cardiovascular disorders. 22(1) |
| ISSN: | 1471-2261 |
| Popis: | Background Blood lipids are strong risk factors for the progression of atherosclerotic plaques. However, data on gender-specific associations are limited. Objectives To examine gender-specific associations of coronary plaque with blood lipids among a large sample of Saudi patients without CAD. Methods Retrospective cross-sectional study was conducted among adult patients referred to (64 multidetector spiral) computed tomography (CT) for standard indications at the Prince Sultan Cardiac Centre (Riyadh, Saudi Arabia) between July 2007 and December 2017. Those with pre-existing CAD were excluded. Plaques were determined based on quantification of coronary calcium and Coronary CT angiography. Results A total 2421 patients (1498 males and 923 females) were included. The prevalence of any plaque was 36.6% with higher burden in males than females (41.3% versus 28.9%, p Conclusions Middle-aged patients without clinical CAD in Saudi Arabia have a high burden of plaques, specially calcified ones. The findings may impact the use of lipid lowering mediations, by underscoring the importance of assessing the risk of CAD in patients without clinical CAD even in case of lack of coronary calcification. |
| Databáze: | OpenAIRE |
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