Circadian phase and intertrial interval interfere with social recognition memory
| Autor: | Gilberto Fernando Xavier, João Antonio Gimenes-Júnior, Paula J. Moura, Verónica S. Valentinuzzi |
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| Jazyk: | angličtina |
| Rok vydání: | 2009 |
| Předmět: |
Male
medicine.medical_specialty Circadian phase Time Factors Photoperiod SOCIAL MEMORY Experimental and Cognitive Psychology INACTIVE PHASE Audiology Motor Activity HABITUATION/DIS-HABITUATION PARADIGM Developmental psychology Ciencias Biológicas Behavioral Neuroscience CIRCADIAN PHASE SOCIAL INTERACTION medicine Animals Circadian rhythm SOCIAL BEHAVIORS Habituation Rats Wistar Social Behavior Recognition memory Analysis of Variance Behavior Animal INTRUDER Recognition Psychology Social recognition Social relation Circadian Rhythm Rats Interval (music) INTERTRIAL INTERVAL ACTIVE PHASE RAT RECOGNITION MEMORY Otros Tópicos Biológicos Psychology CIENCIAS NATURALES Y EXACTAS Social behavior RESIDENT |
| Popis: | A modified version of the social habituation/dis-habituation paradigm was employed to examine social recognition memory in Wistar rats during two opposing (active and inactive) circadian phases, using different intertrial intervals (30 and 60 min). Wheel-running activity was monitored continuously to identify circadian phase. To avoid possible masking effects of the light-dark cycle, the rats were synchronized to a skeleton photoperiod, which allowed testing during different circadian phases under identical lighting conditions. In each trial, an infantile intruder was introduced into an adult's home-cage for a 5-minute interaction session, and social behaviors were registered. Rats were exposed to 5 trials per day for 4 consecutive days: on days 1 and 2, each resident was exposed to the same intruder; on days 3 and 4, each resident was exposed to a different intruder in each trial. The resident's social investigatory behavior was more intense when different intruders were presented compared to repeated presentation of the same intruder, suggesting social recognition memory. This effect was stronger when the rats were tested during the inactive phase and when the intertrial interval was 60 min. These findings suggest that social recognition memory, as evaluated in this modified habituation/dis-habituation paradigm, is influenced by the circadian rhythm phase during which testing is performed, and by intertrial interval. Fil: Moura, Paula J.. Universidade de Sao Paulo; Brasil Fil: Gimenes Júnior, João A.. Universidade de Sao Paulo; Brasil Fil: Valentinuzzi, Verónica Sandra. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Regional de Investigaciones Científicas y Transferencia Tecnológica de La Rioja. - Universidad Nacional de La Rioja. Centro Regional de Investigaciones Científicas y Transferencia Tecnológica de La Rioja. - Universidad Nacional de Catamarca. Centro Regional de Investigaciones Científicas y Transferencia Tecnológica de La Rioja. - Secretaría de Industria y Minería. Servicio Geológico Minero Argentino. Centro Regional de Investigaciones Científicas y Transferencia Tecnológica de La Rioja. - Provincia de La Rioja. Centro Regional de Investigaciones Científicas y Transferencia Tecnológica de La Rioja; Argentina Fil: Xavier, Gilberto F.. Universidade de Sao Paulo; Brasil |
| Databáze: | OpenAIRE |
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