P300 and executive function alterations: possible links in a case of Morgagni-Stewart-Morel syndrome
| Autor: | Stefano Sotgiu, I. Magnano, Giulio Rosati, A. R. Casu, Kai Stephan Paulus, Isidoro Aiello, M.R. Piras, GianPietro Sechi, R. Cherchi |
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| Rok vydání: | 2002 |
| Předmět: |
medicine.medical_specialty
Neurology genetic structures Dermatology behavioral disciplines and activities medicine Humans Neuroradiology Morgagni Stewart Morel syndrome Neuropsychology Cognition General Medicine Middle Aged medicine.disease Event-Related Potentials P300 Frontal Lobe Psychiatry and Mental health Frontal lobe Frontal Bone Female Neurology (clinical) Hyperostosis frontalis interna Cognition Disorders Psychology Hyperostosis Frontalis Interna Neuroscience Executive dysfunction |
| Zdroj: | Neurological Sciences. 22:459-462 |
| ISSN: | 1590-3478 1590-1874 |
| DOI: | 10.1007/s100720200006 |
| Popis: | To evaluate possible cause-effect relationships between hyperostosis frontalis interna and cognitive dysfunction, we performed a neurophysiological (event-related potentials, ERPs) and neuropsychological study in a case of Morgagni-Stewart-Morel (MSM) syndrome associated with frontal lobe compression. Neuropsychological evaluation evidenced selective impairment of executive function. Visual and auditory oddball ERPs revealed delayed P300 latency and reduced auditory P300 amplitude with multi-peaked morphology. ERP abnormalities and cognitive dysfunction could be due to the frontal bone-cortex conflict documented by neuroradiological investigations. |
| Databáze: | OpenAIRE |
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