Tumor Growth Parameters Estimation and Source Localization From a Unique Time Point: Application to Low-grade Gliomas

Autor: Erin Stretton, Hervé Delingette, Olivier Clatz, Ezequiel Geremia, Islem Rekik, Stéphanie Allassonnière, Nicholas Ayache
Přispěvatelé: Analysis and Simulation of Biomedical Images (ASCLEPIOS), Inria Sophia Antipolis - Méditerranée (CRISAM), Institut National de Recherche en Informatique et en Automatique (Inria)-Institut National de Recherche en Informatique et en Automatique (Inria), Centre de Mathématiques Appliquées - Ecole Polytechnique (CMAP), École polytechnique (X)-Centre National de la Recherche Scientifique (CNRS), European Project: 291080,EC:FP7:ERC,ERC-2011-ADG_20110209,MEDYMA(2012)
Jazyk: angličtina
Rok vydání: 2013
Předmět:
Zdroj: Computer Vision and Image Understanding
Computer Vision and Image Understanding, 2013, 117 (3), pp.238--249. ⟨10.1016/j.cviu.2012.11.001⟩
ISSN: 1077-3142
1090-235X
DOI: 10.1016/j.cviu.2012.11.001⟩
Popis: International audience; Coupling time series of MR Images with reaction-di usion-based models has provided interesting ways to better understand the proliferative-invasive as- pect of glial cells in tumors. In this paper, we address a di erent formulation of the inverse problem: from a single time point image of a non-swollen brain tumor, estimate the tumor source location and the di usivity ratio between white and grey matter, while exploring the possibility to predict the further extent of the observed tumor at later time points in low-grade gliomas. The synthetic and clinical results show the stability of the located source and its varying distance from the tumor barycenter and how the estimated ratio controls the spikiness of the tumor.
Databáze: OpenAIRE