Development of Pyothorax-Associated Pleural Lymphoma in Relation to Focal Cytokinemic Condition and Epstein-Barr Virus Infection
| Autor: | Shigeru Shionoya, Isao Okayasu, Yasuo Takano, Mikio Danbara, Yumi Fujino |
|---|---|
| Rok vydání: | 1998 |
| Předmět: |
Male
Herpesvirus 4 Human Pathology medicine.medical_specialty medicine.disease_cause Virus Pleural Lymphoma Pleural disease hemic and lymphatic diseases medicine Humans Epstein–Barr virus infection Empyema Pleural Aged business.industry Lymphoma Non-Hodgkin Respiratory disease Herpesviridae Infections Hematology General Medicine medicine.disease Epstein–Barr virus Chromosome Banding Lymphoma Non-Hodgkin's lymphoma Tumor Virus Infections Cytokines RNA Viral business |
| Zdroj: | Acta Haematologica. 99:41-44 |
| ISSN: | 1421-9662 0001-5792 |
| DOI: | 10.1159/000040715 |
| Popis: | We report an initial case of pyothorax-associated pleural lymphoma (PAPL) in which the level of interleukin 6 (IL-6) was remarkably high in the pleural fluid contaminated with tumor cells; at the same time Epstein-Barr virus (EBV)-encoded small RNAs (EBERs) were detected in the lymphoma cells by in situ hybridization. These findings suggest the possibility that EBV-transformed B cells proliferated in the focal cytokinemic condition caused by long-standing chronic inflammation of the pleura and give us a clue to the lymphoma genesis of PAPL. |
| Databáze: | OpenAIRE |
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