Phytochemical Constituents, Antimalarial Efficacy, and Protective Effect of Eucalyptus camaldulensis Aqueous Leaf Extract in Plasmodium berghei-Infected Mice
| Autor: | Akpovwehwee A. Anigboro, Cletus Ozege Cholu, Oghenetega J. Avwioroko |
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| Jazyk: | angličtina |
| Rok vydání: | 2020 |
| Předmět: |
0301 basic medicine
antimalarial potential 030231 tropical medicine Saponin Parasitemia Article Terpene 03 medical and health sciences 0302 clinical medicine phytochemical compositions renal protection parasitic diseases medicine Tannin Plasmodium berghei Eucalyptus camaldulensis chemistry.chemical_classification Nutrition and Dietetics Traditional medicine biology Therapeutic effect medicine.disease biology.organism_classification 030104 developmental biology chemistry Phytochemical liver protection Food Science |
| Zdroj: | Preventive Nutrition and Food Science |
| ISSN: | 2287-8602 2287-1098 |
| Popis: | This study examined the bioactive components of Eucalyptus camaldulensis aqueous leaf extracts and their protective effects on liver and renal function in a Plasmodium berghei-induced albino mouse model of malarial infection. The results showed that E. camaldulensis extracts are rich in phytochemicals, including flavonoids, phenols, saponin, terpenes, and tannin. Four days after infection with malaria, elevated parasitemia levels in untreated control mice dropped by 4.57%. Administration of E. camaldulensis extracts at doses of 100, 200, and 300 mg/kg significantly decreased parasitemia levels by 17.39, 61.88, and 60.53%, respectively (all P |
| Databáze: | OpenAIRE |
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