Isolated diffusing capacity reduction is a common clinical presentation in deployed Iraq and Afghanistan veterans with deployment-related environmental exposures

Autor: Lydia A. Patrick-DeLuca, Drew A. Helmer, Duncan Ndirangu, Omowunmi Y. Osinubi, Michael J. Falvo, Anays Sotolongo, Jacquelyn C. Klein
Rok vydání: 2016
Předmět:
Adult
Lung Diseases
Male
Pulmonary and Respiratory Medicine
Spirometry
medicine.medical_specialty
Time Factors
Respiratory Tract Diseases
Risk Assessment
Severity of Illness Index
Tertiary care
Pulmonary function testing
Cohort Studies
Young Adult
03 medical and health sciences
0302 clinical medicine
DLCO
Diffusing capacity
Humans
Immunology and Allergy
Medicine
030212 general & internal medicine
Iraq War
2003-2011

Genetics (clinical)
Retrospective Studies
Veterans
Lung
Afghan Campaign 2001
medicine.diagnostic_test
business.industry
Incidence
Pulmonary Diffusing Capacity
Environmental Exposure
Middle Aged
respiratory system
Prognosis
medicine.disease
humanities
Respiratory Function Tests
Military Personnel
medicine.anatomical_structure
030228 respiratory system
Emergency medicine
Female
Medical emergency
Presentation (obstetrics)
business
Zdroj: The Clinical Respiratory Journal. 12:795-798
ISSN: 1752-6981
Popis: Following deployment to Iraq and Afghanistan ("post-9/11"), a spectrum of respiratory conditions has been reported; however, there are few published reports of objective physiologic data or later experience of symptoms and function. To better understand the post-deployment clinical presentation, we conducted a retrospective review of pulmonary function testing in 143 veterans referred to our tertiary care clinic for post-deployment health concerns. More than 75% of our sample had normal lung volumes and spirometry on pulmonary function testing; however, an isolated reduction in lung diffusing capacity (DLCO) was observed in 30% of our sample of post-9/11 veterans. An isolated reduction in DLCO is a rare pattern in primary-care seeking dyspneic patients, but is commonly associated with underlying pulmonary disease. Post-9/11 veterans with respiratory complaints and an isolated reduction in DLCO should undergo further evaluation.
Databáze: OpenAIRE