Heart defibrillation: relationship between pacing threshold and defibrillation probability
Autor: | Isabella Bonilha, Priscila Correia Antoneli, Daniela Diógenes de Carvalho, Pedro Xavier de Oliveira, Jair Trapé Goulart |
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Rok vydání: | 2019 |
Předmět: |
Male
medicine.medical_specialty lcsh:Medical technology Time Factors Defibrillation 030310 physiology medicine.medical_treatment Electric Countershock Biomedical Engineering 030204 cardiovascular system & hematology Biomaterials 03 medical and health sciences 0302 clinical medicine Internal medicine Animals Medicine Myocytes Cardiac Radiology Nuclear Medicine and imaging Ventricular fibrillation Rats Wistar Electric stimulation Probability Fibrillation 0303 health sciences Radiological and Ultrasound Technology business.industry Pulse (signal processing) Research Pulse duration Heart General Medicine medicine.disease Isolated rat heart preparation Rats Intensity (physics) lcsh:R855-855.5 Shock (circulatory) Cardiology Safety medicine.symptom business |
Zdroj: | BioMedical Engineering BioMedical Engineering OnLine, Vol 18, Iss 1, Pp 1-12 (2019) |
ISSN: | 1475-925X |
DOI: | 10.1186/s12938-019-0715-5 |
Popis: | Background Considering the clinical importance of the ventricular fibrillation and that the most used therapy to reverse it has a critical side effect on the cardiac tissue, it is desirable to optimize defibrillation parameters to increase its efficiency. In this study, we investigated the influence of stimuli duration on the relationship between pacing threshold and defibrillation probability. Results We found out that 0.5-ms-long pulses had a lower ratio of defibrillation probability to the pacing threshold, although the higher the pulse duration the lower is the electric field intensity required to defibrillate the hearts. Conclusion The appropriate choice of defibrillatory shock parameters is able to increase the efficiency of the defibrillation improving the survival chances after the occurrence of a severe arrhythmia. The relationship between pulse duration and the probability of reversal of fibrillation shows that this parameter cannot be underestimated in defibrillator design since different pulse durations have different levels of safety. |
Databáze: | OpenAIRE |
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