Multi-Component Sequential Synthesis of Dihydroorotic Acid-Based Amphiphilic Molecules

Autor:	Volonterio, A., Sani, M., Bellucci, M. C.
Rok vydání:	2022
Předmět:	antibacterial domino process multicomponent reactions Organic Chemistry amphiphilic molecules cationic lipids Catalysis
Zdroj:	Synthesis. 54:5311-5323
ISSN:	1437-210X 0039-7881
Popis:	An efficient multicomponent sequential process, which occurs in mild condition has been exploited for the synthesis of systematically modified amphiphilic molecules where the cationic head is tethered to a lipophilic tail through a dihydroorotic acid linker. The process is operatively simple, high yielding, and flexible. Such a strategy could impact combinatorial synthesis of wide libraries of amphiphilic molecules to be tested as transfection agents and/or as antimicrobials.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9b4bbae547b3925ba6ef20f2267d8f6a https://doi.org/10.1055/a-1913-3105 Zobrazit plný text záznamu