Neonatal sepsis and mortality in a regional hospital in Trinidad: aetiology and risk factors
| Autor: | Simone M. Shurland, Fitzroy A. Orrett |
|---|---|
| Rok vydání: | 2001 |
| Předmět: |
Male
Pediatrics medicine.medical_specialty Hospitals Rural 030231 tropical medicine Population Ceftazidime Sepsis 03 medical and health sciences 0302 clinical medicine 030225 pediatrics Infant Mortality medicine Humans Infection control Pseudomonas Infections Hospital Mortality Risk factor education Cross Infection education.field_of_study Neonatal sepsis business.industry Incidence (epidemiology) Infant Newborn Bacterial Infections Staphylococcal Infections medicine.disease Trinidad and Tobago Pediatrics Perinatology and Child Health Ampicillin Drug Therapy Combination Female Gentamicin Gentamicins business Infant Premature medicine.drug |
| Zdroj: | Annals of Tropical Paediatrics. 21:20-25 |
| ISSN: | 1465-3281 0272-4936 |
| DOI: | 10.1080/02724930020028867 |
| Popis: | A total of 132 neonatal deaths among 627 infants admitted to the neonatal ward of the San Fernando General Hospital, Trinidad over a 2-year period were reviewed. The most common cause of death was prematurity (43.9%). Infection was the second most common cause (21.2%). Pseudomonas aeruginosa and Staphylococcus aureus were the most frequently isolated organisms (43%). The major drugs used empirically in suspected cases of sepsis were ampicillin or ceftazidime plus gentamicin. About 85% of S. aureus were resistant to ampicillin, and P. aeruginosa resistance to ceftazidime and gentamicin was 76.7% and 72.1%, respectively. Significant risk factors in maternal history were infrequent antenatal care and prolonged rupture of membranes. The incidence of infection among low birthweight infants was 85.6%. Early-onset sepsis (86.4%) seemed to have a nosocomial origin because of the type of pathogens seen. There is an urgent need to improve the staff-to-patient ratio in the neonatal unit and for staff to be constantly reminded to employ simple infection control practices such as proper hand-washing to reduce cross-infections. |
| Databáze: | OpenAIRE |
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