Algorithm of ovulation induction in patients with polycistic ovary syndrome
| Autor: | Bjelanović J, Ilić Đ, Milić N, Dimitrijević J, Mladenović Segedi L, Artur Bjelica |
|---|---|
| Rok vydání: | 2016 |
| Předmět: |
Infertility
medicine.medical_specialty Ovarian drilling Reproductive Techniques Assisted medicine.medical_treatment media_common.quotation_subject 030209 endocrinology & metabolism Ovary Clomiphene Anovulation 03 medical and health sciences 0302 clinical medicine Ovulation Induction Pregnancy Nitriles medicine Humans Hypoglycemic Agents Ovulation media_common Gynecology 030219 obstetrics & reproductive medicine Aromatase Inhibitors business.industry Fertility Agents Female General Medicine Triazoles medicine.disease Polycystic ovary Metformin medicine.anatomical_structure Letrozole Female Ovulation induction Literature survey business Infertility Female Algorithm Algorithms Gonadotropins Polycystic Ovary Syndrome |
| Zdroj: | Medical review. 69:25-30 |
| ISSN: | 1820-7383 0025-8105 |
| DOI: | 10.2298/mpns1602025b |
| Popis: | Introduction. Polycystic ovary syndrome is the most frequent endocrine disturbance in the reproductive period of women’s life and the most frequent cause of anovulatory infertility. Ovulation and pregnancy in patients having polycystic ovary syndrome may be a result of a wide range of therapeutic options, and the treatment assumes a gradual approach - from simple noninvasive to expensive and demanding procedures. Material and Methods. A systematic literature survey concerning the efficiency of particular ovulation induction methods in respect of the reproductive outcome was carried out with the aim of establishing the algorithm for ovulation induction in infertile patients having polycystic ovary syndrome. The search was confined to clinical investigations performed on human subjects, reported in English in the period from the beginning of 2010 to June of 2014. Conclusion. As a conclusion of this systematic survey of the efficiency of ovulation induction methods, which confirms and supplements the knowledge in this field, it is possible to form the algorithm for ovulation induction in infertile patients having polycystic ovary syndrome, consisting of the following subsequent steps: 1) modification of life style, 2) induction with clomiphene citrate 3) use of metformin, 4) use of aromatase inhibitors, 5) application of gonadotropins and laparoscopic ovarian drilling - as a second-line treatment, and 6) assisted reproductive techniques. |
| Databáze: | OpenAIRE |
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