The value of dynamic contrast-enhanced magnetic resonance imaging combined with apparent diffusion coefficient in the differentiation of benign and malignant diseases of the breast
| Autor: | Feng Ao, Guang-Bin Chen, Wen-Jing Li, Yi Yan, Sheng Li, Zi-Li Zhang |
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| Rok vydání: | 2021 |
| Předmět: |
Contrast Media
Breast Neoplasms Sensitivity and Specificity 030218 nuclear medicine & medical imaging Diagnosis Differential 03 medical and health sciences 0302 clinical medicine Nuclear magnetic resonance Breast cancer Humans Effective diffusion coefficient Medicine Radiology Nuclear Medicine and imaging Breast skin and connective tissue diseases Retrospective Studies Radiological and Ultrasound Technology medicine.diagnostic_test business.industry Magnetic resonance imaging Syndrome General Medicine medicine.disease Magnetic Resonance Imaging Dynamic contrast Diffusion Magnetic Resonance Imaging 030220 oncology & carcinogenesis Female Breast disease business Value (mathematics) Diffusion MRI |
| Zdroj: | Acta Radiologica. 63:891-900 |
| ISSN: | 1600-0455 0284-1851 |
| Popis: | Background The value of combined dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI) and apparent diffusion coefficient (ADC) histogram analysis for the diagnosis of breast cancer has not been evaluated in previous studies. Purpose To investigate the diagnostic value of DCE-MRI combined with ADC in benign and malignant breast lesions. Material and Methods The clinicopathological imaging data included 168 patients (177 lesions) with breast lesions who underwent convention breast MRI, DCE-MRI, and diffusion-weighted imaging (DWI); they were divided into the benign lesion group (n = 39) and malignant lesion group (n = 129) based on pathology. Results Using the type III outflow curve as a diagnostic criterion for malignant breast lesions, the diagnostic sensitivity was 76.9%, the specificity was 80%, the correct rate was 72.2%, and its area under the curve (AUC) was 0.823. Using an enhancement ratio > 100% as a diagnostic criterion for malignant breast lesions, the sensitivity was 61.5%, specificity was 80%, and AUC was 0.723. Using > 3 ipsilateral vessels as a diagnostic criterion for malignant lesions in the breast resulted in a diagnostic sensitivity of 81.6%, a specificity of 80.8%, and an AUC of 0.805. Conclusion The type of time intensity curve DCE-MRI, the early enhancement rate in the first phase, the number of ipsilateral vessels, and the ADC full volume histogram of the blood supply score and DWI are valuable in the diagnosis of benign and malignant breast lesions. |
| Databáze: | OpenAIRE |
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