A systematic review and consensus definitions for standardised end-points in perioperative medicine : pulmonary complications
Autor: | Bilal Alkhaffaf, Christopher L. Wu, M. Gabreu, Alexander J. Fowler, Tony Gin, S. Dieleman, P. Peyton, D. Jamie Cooper, Tong J. Gan, Tomas Corcoran, Simon K. Jackson, Oliver Boney, D. van Dijk, Nathan L. Pace, G. S. De Oliveira, Martin R. Tramèr, Luca Cabrini, Michael P. Murphy, Timothy G. Short, Giovanni Landoni, Ronald B. George, Henrik Kehlet, David Mazer, Ulrica Nilsson, Cornelis J. Kalkman, Rupert M Pearse, R. Eckenhoff, Andrea Kurz, Monty G. Mythen, N. Stevenson, David R. McIlroy, Lis Evered, M.-B. Jensen, Manoj M. Lalu, Russell L. Gruen, R. Sneyd, Stephen Morris, Meghan B. Lane-Fall, Ramani Moonesinghe, D. I. Sessler, Guy Haller, Michael P.W. Grocott, Paul S. Myles, Mark D. Johnson, Ben Creagh-Brown, E. Diouf, Marcus J. Schultz, Ann Merete Møller, Lars Eriksson, Tom E.F. Abbott, Peter Nagele, Andrew A. Klein, Paolo Pelosi, A. Cyna, Lee A. Fleisher, Mark A Shulman, David A Story, Andrew D. Shaw, Sohail Bampoe, W. A. van Klei, Timothy E. Miller, Justyna Bartoszko, M. Gama de Abreu, Scott Beattie, Vijaya Gottumukkala, Brendan S. Silbert, Toby Richards, Michael P. W. Grocott, Bernhard Riedel, Mari Botti, Tim Cook, J. Billings, Lars S. Rasmussen, Andre Lamy, Keyvan Karkouti, Mark D. Neuman, John R. Prowle, Jaume Canet, Matthew T. V. Chan, David Scott, Bruce M Biccard, Donal J. Buggy, Emmanuel Futier, Simon J. Howell, Duminda N. Wijeysundera, Kate Leslie, Hilary P. Grocott, M. Jayarajah, Rinaldo Bellomo |
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Přispěvatelé: | Abbott, Tef, Fowler, Aj, Pelosi, P, Gama de Abreu, M, Møller, Am, Canet, J, Creagh-Brown, B, Mythen, M, Gin, T, Lalu, Mm, Futier, E, Grocott, Mp, Schultz, Mj, Pearse, Rm, and the StEP-COMPAC, Group, Landoni, Giovanni, Haller, Guy Serge Antoine |
Jazyk: | angličtina |
Rok vydání: | 2018 |
Předmět: |
Lung Diseases
Research design medicine.medical_specialty Consensus MEDLINE outcome assessment (healthcare)/standard Perioperative Care law.invention Outcome Assessment (Health Care) 03 medical and health sciences Postoperative Complications 0302 clinical medicine Randomized controlled trial perioperative care/method 030202 anesthesiology law Anesthesiology Outcome Assessment Health Care Positive airway pressure Health care medicine outcome assessment (healthcare)/standards perioperative care/methods Humans Randomized Controlled Trials as Topic Reference Standards Research Design Anesthesiology and Pain Medicine 030212 general & internal medicine Intensive care medicine Perioperative medicine ddc:617 Manchester Cancer Research Centre business.industry ResearchInstitutes_Networks_Beacons/mcrc Perioperative business |
Zdroj: | British Journal of Anaesthesia, 120(5), 1066. Oxford University Press The StEP-COMPAC Group 2018, ' A systematic review and consensus definitions for standardised end-points in perioperative medicine : pulmonary complications ', British Journal of Anaesthesia, vol. 120, no. 5, pp. 1066-1079 . https://doi.org/10.1016/j.bja.2018.02.007 British journal of anaesthesia, Vol. 120, No 5 (2018) pp. 1066-1079 |
ISSN: | 0007-0912 |
DOI: | 10.1016/j.bja.2018.02.007 |
Popis: | Background: There is a need for robust, clearly defined, patient-relevant outcome measures for use in randomised trials in perioperative medicine. Our objective was to establish standard outcome measures for postoperative pulmonary complications research.Methods: A systematic literature search was conducted using MEDLINE, Web of Science, SciELO, and the Korean Journal Database. Definitions were extracted from included manuscripts. We then conducted a three-stage Delphi consensus process to select the optimal outcome measures in terms of methodological quality and overall suitability for perioperative trials.Results: From 2358 records, the full texts of 81 manuscripts were retrieved, of which 45 met the inclusion criteria. We identified three main categories of outcome measure specific to perioperative pulmonary outcomes: (i) composite outcome measures of multiple pulmonary outcomes (27 definitions); (ii) pneumonia (12 definitions); and (iii) respiratory failure (six definitions). These were rated by the group according to suitability for routine use. The majority of definitions were given a low score, and many were imprecise, difficult to apply consistently, or both, in large patient populations. A small number of highly rated definitions were identified as appropriate for widespread use. The group then recommended four outcome measures for future use, including one new definition.Conclusions: A large number of postoperative pulmonary outcome measures have been used, but most are poorly defined. Our four recommended outcome measures include a new definition of postoperative pulmonary complications, incorporating an assessment of severity. These definitions will meet the needs of most clinical effectiveness trials of treatments to improve postoperative pulmonary outcomes. |
Databáze: | OpenAIRE |
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