Predictors of health-related quality of life in neurosurgical brain tumor patients: focus on patient-centered perspective
| Autor: | Arimantas Tamašauskas, Adomas Bunevicius, Robertas Bunevičius, Vytenis Pranas Deltuva, Andrius Radziunas, Sarunas Tamasauskas |
|---|---|
| Rok vydání: | 2013 |
| Předmět: |
Adult
Male medicine.medical_specialty media_common.quotation_subject Emotions Anxiety Severity of Illness Index Cognition Quality of life Surveys and Questionnaires Severity of illness medicine Humans Personality Big Five personality traits Psychiatry Depression (differential diagnoses) Aged media_common Aged 80 and over Brain Neoplasms Depression business.industry Middle Aged humanities Quality of Life Female Surgery Neurology (clinical) Neurosurgery medicine.symptom business |
| Zdroj: | Acta Neurochirurgica. 156:367-374 |
| ISSN: | 0942-0940 0001-6268 |
| DOI: | 10.1007/s00701-013-1930-7 |
| Popis: | In brain tumor (BT) patients, the association between health-related quality of life (HRQoL) and psychological characteristics remains largely unknown. We evaluated the association of personality traits, clinical factors, psychological distress symptoms, and cognitive state with HRQoL in BT patients.On admission for BT surgery, 200 patients (69 % women; age 55.8 ± 14.5 years) were evaluated for HRQoL (SF-36 scale), Big-Five personality traits (Ten-Item Personality Inventory), psychological distress symptoms (Hospital Anxiety and Depression Scale or HADS), cognitive function (Mini-Mental State Examination or MMSE) and clinical characteristics, including functional status (Barthel index or BI). The most common BT diagnoses were meningioma (39 %) and high-grade glioma (18 %).Only factors significantly associated with SF-36 domains in univariable regression analyses were included in their respective multivariable models and predicted from 6 %-49 % of the total variance of SF-36 scores. Greater TIPI emotional stability score was independently associated with greater SF-36 emotional well-being (β = 0.23, p 0.001) and general health (β = 0.18, p = 0.01) scores, and greater TIPI consciousness score, with greater SF-36 emotional well-being score (β = 0.13, p = 0.02). HADS-anxiety and HADS-depression scores were the strongest independent determinants of all, except physical functioning, SF-36 scores (β-values range from 0.14 to 0.56; p values ≤ 0.03). BI score was the strongest independent determinant of SF-36 physical functioning score (β = 0.36, p 0.001). MMSE score was associated with all but emotional well-being and social functioning SF-36 scores.Consciousness and emotional stability should be considered important personality-related determinants of HRQoL in BT patients. Psychological distress, functional disability, and cognitive impairment are also important predictors of HRQoL. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|
Full text from SpringerLink