Aerosolization of Mycobacterium avium and Mycobacterium abscessus from a household ultrasonic humidifier
| Autor: | Lindsay A. Hamilton, Joseph O. Falkinham |
|---|---|
| Rok vydání: | 2018 |
| Předmět: |
0301 basic medicine
Microbiology (medical) 030106 microbiology Pulmonary disease Fresh Water Mycobacterium abscessus Microbiology Humidifiers Human lung 03 medical and health sciences medicine Aerosolization Mycobacterium avium subspecies hominissuis Aerosols biology Mycobacterium abscessus subsp. abscessus General Medicine bacterial infections and mycoses biology.organism_classification 030104 developmental biology medicine.anatomical_structure Air Pollution Indoor Equipment Contamination bacteria Mycobacterium avium Mycobacterium |
| Zdroj: | Journal of Medical Microbiology. 67:1491-1495 |
| ISSN: | 1473-5644 0022-2615 |
| DOI: | 10.1099/jmm.0.000822 |
| Popis: | Purpose. To measure the aerosolization of Mycobacterium avium subspecies hominissuis and Mycobacterium abscessus subspecies abscessus from ultrasonic humidifiers. Methodology. An ultrasonic humidifier was filled with sterile tap water and inoculated with water-acclimated cells of either the M. avium or M. abscessus strains to achieve a range of densities similar to those of mycobacteria found in drinking waters. During operation of the humidifier, aerosols were collected using an Andersen 6-Stage Cascade Sampler. Results. Cells of the M. avium and M. abscessus strains were readily aerosolized and recovered in particles (1–5 µm diameter); small enough to enter the furthest reaches of the human lung. Aerosolization of M. abscessus was significantly reduced in the presence of a normal drinking water bacterial flora. Significantly greater numbers of M. avium cells were aerosolized from high-density suspensions (1200 c.f.u. ml−1), than from low-density (120 c.f.u. ml−1) and very low-density (12 c.f.u. ml−1) suspensions. Conclusions. This report documents the potential for M. avium subspecies hominissuis and M. abscessus subspecies abscessus cells in drinking water to be aerosolized from one type of portable humidifier; an ultrasonic humidifier. Care should be taken in using an ultrasonic humidifier where an individual at risk for mycobacterial pulmonary disease could be exposed. |
| Databáze: | OpenAIRE |
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