Isobaric 6-plex and tosyl dual tagging for the determination of positional isomers and quantitation of monounsaturated fatty acids using rapid UHPLC-MS/MS

Autor:	Michael R. Armbruster, Mahmoud Elhusseiny Mostafa, Rhea N. Caldwell, Scott F. Grady, Christopher K. Arnatt, James L. Edwards
Rok vydání:	2022
Předmět:	Electrochemistry Environmental Chemistry Biochemistry Spectroscopy Analytical Chemistry
Zdroj:	The Analyst.
ISSN:	1364-5528
Popis:	Isobaric labelling of fatty acids is complicated by chromatographic co-elution of double bond isomers. This produces contaminated spectra which can mask important biological changes. Here two derivatization strategies are combined to improve throughput and produce MS
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9b19a7056d3af150b09a8e863d78dbf2 https://pubmed.ncbi.nlm.nih.gov/36533920 Zobrazit plný text záznamu