VISIBLE LIGHT ANAEROBIC PHOTOCONVERSION OF TYROSINE SENSITIZED BY RIBOFLAVIN. CYTOTOXICITY ON MOUSE TUMORAL CELLS
Autor: | Alfredo E. De Ioannes, M. Ines Becker, Eduardo Silva, Sonia Fürst, Ana María Edwards |
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Rok vydání: | 2008 |
Předmět: |
Myeloid
Light Photochemistry Riboflavin Absorption (skin) Biochemistry Mice Tumor Cells Cultured medicine Animals Drug Interactions Anaerobiosis Physical and Theoretical Chemistry Tyrosine Cytotoxicity Chemistry General Medicine Phototherapy Aerobiosis medicine.anatomical_structure Leukemia Myeloid biological sciences sense organs Anaerobic exercise Visible spectrum |
Zdroj: | Photochemistry and Photobiology. 62:1041-1045 |
ISSN: | 1751-1097 0031-8655 |
DOI: | 10.1111/j.1751-1097.1995.tb02406.x |
Popis: | The anaerobic phototransformation of tyrosine under visible light sensitized by riboflavin is reported. The cytotoxicity of the anaerobic photoproducts on in vitro-cultured myeloid mouse tumoral cells was demonstrated. A radical mechanism is proposed. Dityrosine was identified as one of the main anaerobic photoproducts by using absorption, emission and 1H-NMR spectra. |
Databáze: | OpenAIRE |
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