The relationship between lesion density change in chest computed tomography and clinical improvement in COVID-19 patients
Autor: | Suleyman Hilmi Aksoy, Fuad Nurili, Isil Yurdaisik, Ayse Gul Agirman |
---|---|
Přispěvatelé: | Aksoy, Süleyman Hilmi |
Jazyk: | angličtina |
Rok vydání: | 2021 |
Předmět: |
Adult
Male medicine.medical_specialty Cross-sectional study Therapy area: Other ORIGINAL PAPERS 030204 cardiovascular system & hematology Ground-glass opacity Lesion 03 medical and health sciences 0302 clinical medicine White blood cell Hounsfield scale Humans Medicine 030212 general & internal medicine Lung Retrospective Studies Klinik Özellikler Original Paper Clinical Features SARS-CoV-2 business.industry Radiological Findings COVID-19 Retrospective cohort study General Medicine Middle Aged Cross-Sectional Studies medicine.anatomical_structure Radiological weapon Radyolojik Bulgular Radiology medicine.symptom Tomography X-Ray Computed business |
Zdroj: | International Journal of Clinical Practice |
Popis: | Objective To evaluate the association of changes in chest computed tomography (CT) lesion densities with clinical improvement in COVID‐19 patients. Methods This was a cross‐sectional analysis of hospitalised COVID‐19 patients who underwent repeated chest CT. Patients who improved clinically but showed radiological progression were included. Demographic data, presentation complaints and laboratory results were retrieved from the electronic database of the hospital. Lesion density that was measured in Hounsfield units was compred between admission and discharge chest CT scans. Results Forty patients (21 males, mean age 47.4 ± 15.1 years) were included in the analysis. The median white blood cell count and C‐reactive protein significantly decreased, whereas the median lymphocyte count significantly increased at discharge compared with the admission values. The mean density significantly reduced from admission to discharge. Conclusion This is the first study in the literature reporting reduction in chest CT lesion densities correlated with clinical and laboratory improvement in COVID‐19 patients. |
Databáze: | OpenAIRE |
Externí odkaz: |