Enhancement of tissue lipoperoxidation in propanil-treated rats
| Autor: | Santangelo F, Norma Staiano, Guglieimo R.D Villani, Mariarosaria Santillo, Paolo Mondola, Carmela Rippa, Rossella Della Morte |
|---|---|
| Přispěvatelé: | Santillo, M. R., Rippa, C., DELLA MORTE, Rossella, Villani, GUGLIELMO ROSARIO DOMENI, Santangelo, F., Staiano, N. AND MONDOLA P., Santillo, Mariarosaria, Rippa, Carmela, Villani, Guglieimo R. D, Santangelo, Franco, Staiano, Norma, Mondola, Paolo |
| Rok vydání: | 1995 |
| Předmět: |
Male
medicine.medical_specialty Propanil Biology Kidney Toxicology Triglyceride Rats Sprague-Dawley Lipid peroxidation chemistry.chemical_compound Microsomes Internal medicine medicine Animals Aspartate Aminotransferases Triglycerides Lipoperoxidation Cholesterol Brain Alanine Transaminase General Medicine Alkaline Phosphatase Rats Endocrinology Liver chemistry Alanine transaminase Toxicity Microsomes Liver Microsome biology.protein Rat Alkaline phosphatase Herbicide Lipid Peroxidation |
| Zdroj: | Toxicology Letters. 78:215-218 |
| ISSN: | 0378-4274 |
| DOI: | 10.1016/0378-4274(95)03257-l |
| Popis: | The i.p. injection of the herbicide propanil to male Sprague-Dawley rats increased the susceptibility to lipoperoxidation of liver and brain rat microsomes. A liver damage produced by propanil treatment was demonstrated by decreased serum levels of cholesterol and triglycerides as compared to serum levels of the lipids in control rats. The cellular damage of rat liver was also confirmed by the increased serum levels of aspartate aminotransferase and alkaline phosphatase activities observed in propanil-treated rats as compared to their activities in control rats. |
| Databáze: | OpenAIRE |
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