A facile and efficient synthesis of 1,8-dioxodecahydroacridines derivatives catalyzed by cobalt–alanine metal complex under aqueous ethanol media
| Autor: | S. Merajuddin Ahmed, Mohammed A. Assiri, Mohammed Mujahid Alam, Ahmed T. Mubarak, Ahmed M. Fouda |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2019 |
| Předmět: |
Cobalt–alanine metal complex
Chemistry Aryl One-pot synthesis Dimedone chemistry.chemical_element General Chemistry Condensation reaction 1 8-Dioxodecahydroacridine Combinatorial chemistry Catalysis lcsh:Chemistry Metal chemistry.chemical_compound lcsh:QD1-999 Ammonium acetate visual_art visual_art.visual_art_medium Multi component reaction (MCR) Cobalt Research Article |
| Zdroj: | BMC Chemistry BMC Chemistry, Vol 13, Iss 1, Pp 1-10 (2019) |
| ISSN: | 2661-801X |
| Popis: | A facile and convenient method for the synthesis of acridines and its derivatives was developed through one-pot, three-component condensation reaction of aromatic aldehydes, 5,5-dimethyl-1,3-cyclohexanedione, aryl amines or ammonium acetates in the presence of a catalytic amount of cobalt–alanine metal complex using aqueous ethanol as a reaction medium is reported. The present described novel methodology offers several advantages over the traditional methods reported in the literature, such as mild reaction conditions, inexpensive catalyst, short reaction times, excellent yields of products, simplicity and easy workup are the advantages of this procedure. |
| Databáze: | OpenAIRE |
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