Pancreatic cyst fluid analysis for differential diagnosis between benign and malignant lesions
| Autor: | Renata Talar-Wojnarowska, Adam Janiak, Piotr Grzelak, Marek Olakowski, Malgorzata Degowska, Ludomir Stefańczyk, Jacek Smigielski, Lukasz Durko, Grażyna Rydzewska, Ewa Małecka-Panas, Paweł Lampe, Marek Pazurek |
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| Rok vydání: | 2012 |
| Předmět: |
Cancer Research
Pathology medicine.medical_specialty amylase biology Intraductal papillary mucinous neoplasm business.industry carcinoembryonic antigen pancreatic cyst Cancer Articles medicine.disease Serous Cystadenoma CA19-9 Carcinoembryonic antigen Oncology parasitic diseases biology.protein Medicine fluid analysis Cyst Pancreatic cysts Differential diagnosis business |
| Zdroj: | Oncology Letters |
| ISSN: | 1792-1074 |
| Popis: | The majority of pancreatic cysts are detected incidentally when abdominal imaging is performed during unrelated procedures. The aim of the present study was to assess the diagnostic utility and clinical value of carcinoembryonic antigen (CEA), carbohydrate antigen 19-9 (CA 19-9) and amylase analysis in pancreatic cyst fluid. The study included 52 patients with pancreatic cystic lesions, who underwent fine-needle aspiration biopsy to collect cystic fluid for cytological and biochemical analysis. Cysts were classified as benign (simple cysts, pseudocysts and serous cystadenomas) in 36 patients or premalignant/malignant (mucinous cyst-adenomas, intraductal papillary mucinous neoplasm and cystadenocarcinomas) in 16 patients. CEA and CA 19-9 were elevated in patients with malignant cysts (238±12.5 ng/ml and 222±31.5 U/ml, respectively) compared with benign lesions (34.5±3.7 ng/ml and 18.5±1.9 U/ml, respectively; P |
| Databáze: | OpenAIRE |
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