Ready for regulatory use : NAMs and NGRA for chemical safety assurance

Autor:	Carmichael, Paul L., Baltazar, Maria T., Cable, Sophie, Cochrane, Stella, Dent, Matthew, Li, Hequn, Middleton, Alistair, Muller, Iris, Reynolds, Georgia, Westmoreland, Carl, White, Andrew
Jazyk:	angličtina
Rok vydání:	2022
Předmět:	Pharmacology Medical Laboratory Technology chemical safety Animals non-animal approaches General Medicine next generation risk assessement (NGRA) Animal Testing Alternatives Toxicology new approach methodologies (NAMs) Risk Assessment Toxicologie
Zdroj:	Altex, 39(3), 359-366 Altex 39 (2022) 3
ISSN:	0946-7785
Popis:	New approach methodologies (NAMs) that do not use experimental animals are, in certain settings, entirely appropriate for assuring the safety of chemical ingredients, although regulatory adoption has been slow. In this opinion article we discuss how scientific advances that utilize NAMs to certify systemic safety are available now and merit broader acceptance within the framework of next generation risk assessments (NGRA).
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9afed46c59fcfa1c58145c164b3f17d7 https://research.wur.nl/en/publications/ready-for-regulatory-use-nams-and-ngra-for-chemical-safety-assura Zobrazit plný text záznamu