Polymeric micelles for anticancer drug delivery
| Autor: | Sudip Kumar Das, Nandita G. Das, Nairrita Majumder |
|---|---|
| Rok vydání: | 2020 |
| Předmět: |
Drug
Drug Carriers Polymeric micelles Chemistry Polymers media_common.quotation_subject Pharmaceutical Science Nanotechnology Antineoplastic Agents 02 engineering and technology 010402 general chemistry 021001 nanoscience & nanotechnology 01 natural sciences Biodegradable polymer Micelle 0104 chemical sciences Drug Delivery Systems Targeted drug delivery Drug delivery Nanomedicine Nanocarriers 0210 nano-technology Micelles media_common |
| Zdroj: | Therapeutic delivery. 11(10) |
| ISSN: | 2041-6008 |
| Popis: | Polymeric micelles have gained interest as novel drug delivery systems for the treatment and diagnosis of cancer, as they offer several advantages over conventional drug therapies. This includes drug targeting to tumor tissue, in vivo biocompatibility and biodegradability, prolonged circulation time, enhanced accumulation, retention of the drug loaded micelle in the tumor and decreased side effects. This article provides an overview on the current state of micellar formulations as nanocarriers for anticancer drugs and their effectiveness in cancer therapeutics, including their clinical status. The type of copolymers used, their physicochemical properties and characterization as well as recent developments in the design of functional polymeric micelles are highlighted. The article also presents the design and outcomes of various types of stimuli-responsive polymeric micelles. |
| Databáze: | OpenAIRE |
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