Cutaneous Alternaria infectoria Infection Diagnosed by Molecular Techniques in a Renal Transplant Patient
| Autor: | Ayşe Akman-Karakaş, Duygu Dağlar, Juan L. Rodriguez-Tudela, Filiz Gunseren, María José Buitrago, Betil Ozhak-Baysan, Mehmet Akif Ciftcioglu |
|---|---|
| Rok vydání: | 2014 |
| Předmět: |
Adult
Male medicine.medical_specialty Pathology Alternaria infectoria Time Factors Itraconazole Opportunistic Infections Real-Time Polymerase Chain Reaction Alternariosis General Biochemistry Genetics and Molecular Biology Organ transplantation law.invention Lesion Immunocompromised Host Predictive Value of Tests law Diabetes mellitus medicine Humans DNA Fungal Polymerase chain reaction Bacteriological Techniques business.industry Alternaria medicine.disease Kidney Transplantation Dermatology Treatment Outcome Increased risk Renal transplant medicine.symptom business Immunosuppressive Agents medicine.drug |
| Zdroj: | Clinical Laboratory. 60 |
| ISSN: | 1433-6510 |
| DOI: | 10.7754/clin.lab.2014.131223 |
| Popis: | Organ transplant recipients under immunosuppressive therapy have a highly increased risk of opportunistic fungal infections. Cutaneous infection caused by Alternaria species are relatively rare in humans and most cases reported in the literature are in immunocompromised individuals. We report here on a 33-year old male renal transplant patient with diabetes mellitus who presented with cutaneous alternariosis caused by Alternaria infectoria, two years after the transplant. The diagnosis was performed by real-time polymerase chain reaction assay and histopathologic examination. The extension of the lesion under itraconazole treatment required treatment consisting of a combination of surgical excision and liposomal amphotericin B. |
| Databáze: | OpenAIRE |
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