Evaluation of the mechanical properties and biocompatibility of gypsum-containing calcium silicate cements
| Autor: | Nobuo Kondoh, Yukimichi Tamaki, Tomoya Hasegawa, Harumi Kawaki, Takakazu Yoshida, Masaharu Hori, Satoshi Kawano, Kohei Shintani, Yumiyo Hayashi, Masashi Tanaka |
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| Rok vydání: | 2021 |
| Předmět: |
Mineral trioxide aggregate
Materials science 0206 medical engineering chemistry.chemical_element Dental Cements 02 engineering and technology Calcium Calcium Sulfate 03 medical and health sciences chemistry.chemical_compound 0302 clinical medicine Dental cement Materials Testing Humans Aluminum Compounds General Dentistry Cement Silicates Oxides 030206 dentistry Calcium Compounds 020601 biomedical engineering Pulp capping Drug Combinations Calcium carbonate Compressive strength chemistry Chemical engineering Calcium silicate Ceramics and Composites Silicate Cement |
| Zdroj: | Dental materials journal. 40(4) |
| ISSN: | 1881-1361 |
| Popis: | Mineral trioxide aggregate (MTA) cement is widely used in the field of endodontic treatment. We herein synthesized calcium silicates from calcium carbonate and silicon dioxide, with the aim of reducing the cost associated with the MTA. Additionally, we prepared gypsum-containing calcium silicate cement to reduce the setting time while enhancing the mechanical strength. We evaluated the physical properties of this cement and investigated the response of human dental pulp stem cells (hDPSCs) grown in culture media containing cement eluate. Our results revealed that calcium silicates could be easily synthesized in lab-scale. Furthermore, we demonstrate that gypsum addition helps shorten the setting time while increasing the compressive strength of dental cements. The synthesized gypsum-containing calcium silicate cement showed minimal cytotoxicity and did not inhibit the proliferation of hDPSCs. These results suggested that the newly developed calcium silicate material could be a promising pulp capping material. |
| Databáze: | OpenAIRE |
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