Successful treatment of a childhood synovitis, acne, pustulosis, hyperostosis and osteitis (SAPHO) syndrome with subcutaneous methotrexate: A case report
| Autor: | Necla Buyan, Emel Isiyel, Enver Hasanoglu, Meltem Akcaboy, Sevcan Azime Bakkaloğlu-Ezgü, Yasar Kandur, Bahar Büyükkaragöz |
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| Jazyk: | angličtina |
| Rok vydání: | 2017 |
| Předmět: |
SAPHO syndrome
Hyperostosis medicine.medical_specialty Injections Subcutaneous 03 medical and health sciences Rare Diseases 0302 clinical medicine Synovitis Humans Medicine 030212 general & internal medicine Child Acne 030203 arthritis & rheumatology Lumbar Vertebrae Dose-Response Relationship Drug business.industry Acquired Hyperostosis Syndrome Remission Induction medicine.disease Pustulosis Magnetic Resonance Imaging Dermatology First line treatment Methotrexate Pediatrics Perinatology and Child Health Female Osteitis medicine.symptom business Immunosuppressive Agents Follow-Up Studies medicine.drug |
| Popis: | Akçaboy M, Bakkaloğlu-Ezgü SA, Büyükkaragöz B, Isıyel E, Kandur Y, Hasanoğlu E, Buyan N. Successful treatment of a childhood synovitis, acne, pustulosis, hyperostosis and osteitis (SAPHO) syndrome with subcutaneous methotrexate: A case report. Turk J Pediatr 2017; 59: 184-188. SAPHO syndrome (synovitis, acne, pustulosis, hyperostosis and osteitis) is defined as a syndrome that is related to various osteoarticular manifestations and chronic dermatological conditions especially severe acne. SAPHO syndrome is a rare and unusual clinical entity in childhood and treatment choices are variable. We report an 11-year-old girl who suffered from SAPHO syndrome and successfully treated with subcutaneous methotrexate. We report our case in order to take attention to this rare clinical condition in evaluating patients and also to point out that treatment options beyond biologic agents should be the first line treatment in childhood. |
| Databáze: | OpenAIRE |
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