Nationwide cross-sectional study of antimicrobial stewardship and antifungal stewardship programs in inpatient settings in Japan
Autor: | Yoshiki Kusama, Yuki Moriyama, Taichi Tajima, Nobuaki Matsunaga, Kayoko Hayakawa, Masahiro Ishikane, Norio Ohmagari |
---|---|
Rok vydání: | 2021 |
Předmět: |
Antifungal
medicine.medical_specialty medicine.drug_class Cross-sectional study Health Personnel Psychological intervention Infectious and parasitic diseases RC109-216 Antimicrobial stewardship Antibiotic resistance Medical microbiology Anti-Infective Agents Japan Surveys and Questionnaires Humans Antifungal stewardship Medicine Cross Infection Internet Inpatients business.industry Antimicrobial Drug Utilization Hospitals Cross-Sectional Studies Infectious Diseases Emergency medicine Stewardship business Program Evaluation Research Article |
Zdroj: | BMC Infectious Diseases, Vol 21, Iss 1, Pp 1-7 (2021) BMC Infectious Diseases |
ISSN: | 1471-2334 |
Popis: | Background To prevent antimicrobial resistance, both antimicrobial stewardship (AMS) and antifungal stewardship (AFS) in inpatient settings are needed in small/middle-sized hospitals as well as large hospitals. Methods We conducted the web-based, self-administered, nationwide cross-sectional study regarding AMS and AFS in inpatient settings in Japan, targeting hospitals that participated in a hospital epidemiology workshop conducted in July 2018. The questionnaire was composed of intervention protocols for use of broad-spectrum antimicrobials and antifungals within 7 or 28 d of beginning usage. These broad-spectrum antimicrobial and antifungal protocols were compared between large (≥501beds) and small/middle-sized (≤500 beds) hospitals. Results Of 240 hospitals surveyed, 39 (16%; 18 large and 21 small/middle-sized) responded. The number of hospitals that intervened in the use of broad-spectrum antimicrobials within 7 and 28 d were 17 (44%) and 34 (87%), respectively; those that intervened for antifungals were 3 (8%) and 10 (26%), respectively. Interventions for use of broad-spectrum antimicrobials within 7 d were significantly more frequent in small/middle-sized hospitals compared to large hospitals [13 (61. 9%) vs. 4 (22. 2%), odds ratio = 5.7, 95% confidence interval = 1.4–23.3, p = 0.023]. Conclusions Small/middle-sized hospitals had more frequent interventions within 7 d of broad-spectrum antimicrobial use than large hospitals. More effort to improve AFS is needed among all hospitals. |
Databáze: | OpenAIRE |
Externí odkaz: |