Optimization of whispering gallery resonator design for biosensing applications

Autor: Shahraam Afshar, Jonathan M. M. Hall, Nicolas Riesen, Tess Reynolds, Tanya M. Monro, Alexandre François, Stephen J. Nicholls, Matthew R. Henderson
Přispěvatelé: Reynolds, T, Henderson, MR, Francois, A, Riesen, N, Hall, JMM, Afshar, SV, Nicholls, SJ, Monro, TM
Jazyk: angličtina
Rok vydání: 2015
Předmět:
Popis: Whispering gallery modes (WGMs) within microsphere cavitiesenable highly sensitive label-free detection of changes in the surroundingrefractive index. This detection modality is of particular interest forbiosensing applications. However, the majority of biosensing work utilizingWGMs to date has been conducted with resonators made from either silicaor polystyrene, while other materials remain largely uninvestigated. Byconsidering characteristics such as the quality factor and sensitivity of theresonator, the optimal WGM sensor design can be identified for variousapplications. This work explores the choice of resonator refractive indexand size to provide design guidelines for undertaking refractive indexbiosensing using WGMs. Refereed/Peer-reviewed
Databáze: OpenAIRE